cenobamate will improve the amount or outcome of diazepam by affecting hepatic enzyme CYP2C19 metabolism. Modify Therapy/Observe Carefully. Look at a dose reduction of CYP2C19 substrates, as clinically appropriate, when applied concomitantly with cenobamate.enasidenib will raise the stage or impact of diazepam by influencing hepatic enzyme CYP2C19